10x
increased risk of a UTI has been found for those receiving botulinum bladder injections.
Bladder treatment with Botulinum Toxin A injections efficiently combats neurogenic bladder overactivity,1 but there is no consensus on UTI rates post injection2 or whether there should be antibiotic coverage for the procedure.3
What do we know from the evidence?
Data is from a spinal cord injury centre, including 1104 patients in a 3-year follow-up period.4
- Soljanik I, Efficacy and safety of botulinum toxin A intradetrusor injections in adults with neurogenic detrusor overactivity/neurogenic overactive bladder: a systematic review. Drugs. 2013;73(10):1055–1066
- Stamm A W, Adelstein S A, Chen A et al., Inconsistency in the definition of urinary tract infection after intravesical botulinum toxin A injection: a systematic review. Journal of Urology. 2018;200(4):809–814
- Mouttalib S, Khan S, Castel-Lacanal E et al., Risk of urinary tract infection after detrusor botulinum toxin A injections for refractory neurogenic detrusor overactivity in patients with no antibiotic treatment. BJU International. 2010;106(11):1677–1680
- Krebs J, Wöllner J, and Pannek J, Urethral strictures in men with neurogenic lower urinary tract dysfunction using intermittent catheterization for bladder evacuation. Spinal Cord. 2015;53(4):310–313